Preheat your grill to medium-high heat.
In a large bowl, combine the ground beef with salt, black pepper, garlic powder, and onion powder.
Form the beef mixture into four equal patties, making a slight indent in the center.
Place the patties on the grill and cook for 4-5 minutes on one side.
Flip the burgers gently and cook for an additional 4-5 minutes, adding cheese if desired.
Remove the burgers from the grill and let them rest for a few minutes.
Toast the burger buns on the grill until golden brown, if desired.
Assemble your burgers with condiments and desired toppings.