Cook the penne pasta until al dente according to package instructions.
In a large skillet, heat olive oil over medium heat.
Add the Italian sausage to the skillet, breaking it up with a spoon as it cooks.
Stir in the minced garlic and cook for another minute until fragrant.
Pour in the heavy cream, stirring to combine with the sausage mixture.
Mix in the grated Parmesan cheese, Italian seasoning, and red pepper flakes.
Season with salt and pepper to taste, adjusting as desired.
Add the cooked penne pasta to the sauce, tossing to combine thoroughly.
Garnish with chopped parsley before serving.