Cheesy Pepperoni Pizza Roll-Ups with Low-Carb Tortillas are the ultimate snack that takes me back to those cozy family pizza nights. I can still remember the excitement as we gathered around the table, the aroma of melting cheese and pepperoni swirling through the air. When I decided to embrace a low-carb lifestyle, I knew I had to recreate that joy in a way that wouldn’t sabotage my diet. These roll-ups are not only quick to prepare but also incredibly satisfying! You’ll adore how the gooey mozzarella melds beautifully with savory pepperoni and zesty pizza sauce, all snuggled up in a soft tortilla. They’re fantastic for a busy day when you need something tasty and filling, or as a fun appetizer for friends. Trust me, whether you’re craving a simple lunch or a delightful party snack, these roll-ups are sure to please everyone. Let’s get cooking!

Why You’ll Love It
- Quick prep time of just 10 minutes—perfect for those busy days!
- Low-carb and keto-friendly option that satisfies your cravings without the guilt.
- Great for meal prep and snacks; make a batch ahead and enjoy throughout the week.
- Kid-friendly and fun to eat—who doesn’t love a cheesy pepperoni pizza roll-up?
- Delicious combination of gooey cheese and savory pepperoni that will have you coming back for more.
- Budget-friendly ingredients mean you can whip these up without breaking the bank.
- Perfect for parties or gatherings—serve them as appetizers, and watch them disappear!
Ingredients for Cheesy Pepperoni Pizza Roll-Ups with Low-Carb Tortillas
- 4 low-carb flour tortillas
- ½ cup pizza sauce, plus extra for dipping
- 1 cup shredded mozzarella cheese
- 16 slices pepperoni
- ½ teaspoon Italian seasoning
- Olive oil cooking spray (optional for crispiness)
For the best results, make sure to use low-carb tortillas—they hold everything together perfectly! You can choose any pizza sauce you like, but I recommend a thicker sauce to keep everything neat and tidy. Feel free to swap out the mozzarella for your favorite cheese if you’re feeling adventurous. The Italian seasoning adds a lovely depth of flavor, but don’t hesitate to skip it or customize with your own favorite herbs!
How to Make Cheesy Pepperoni Pizza Roll-Ups with Low-Carb Tortillas
- Step 1: Preheat your oven to 375°F and line a baking sheet with parchment paper to prevent sticking. This little step will save you from a messy cleanup later!
- Step 2: Place all four tortillas flat on your work surface, making sure they’re at room temperature. This makes them easier to roll without cracking. Trust me, no one likes a broken roll-up!
- Step 3: Spread about 2 tablespoons of pizza sauce evenly on each tortilla, leaving a small border around the edges for rolling. You want a nice saucy layer, but not so much that it spills out!
- Step 4: Sprinkle ¼ cup of mozzarella cheese over the sauce, then arrange 4 pepperoni slices on top. The cheese is what makes these roll-ups so gooey and delicious!
- Step 5: Sprinkle each tortilla with a pinch of Italian seasoning for that extra flavor, then roll each one tightly from one end to the other. Make sure they’re snug, but don’t roll too tight or they might burst!
- Step 6: Place the rolled tortillas seam-side down on the baking sheet. Lightly spray the tops with olive oil for extra crispiness if you’re feeling indulgent.
- Step 7: Bake for 10-12 minutes until the cheese is melted and bubbly, and the tortillas are golden around the edges. Keep an eye on them; you want that perfect golden-brown finish!
- Step 8: Let the roll-ups cool for 2-3 minutes, then slice each into 3-4 pieces. Serve them warm with extra pizza sauce for dipping, and get ready for the compliments to roll in!
Pro Tips for the Best Cheesy Pepperoni Pizza Roll-Ups
- Choose fresh, quality ingredients for the best flavor—trust me, it makes a world of difference!
- Ensure tortillas are at room temperature for easy rolling; cold tortillas can crack and ruin your roll-ups.
- Experiment with different cheeses or toppings for variety—try adding some veggies or switching to a spicy cheese for a fun twist!
- For added crunch, consider broiling the roll-ups for the last minute of baking—just keep an eye on them to avoid burning.
- Don’t forget to let the roll-ups cool slightly after baking; this helps the cheese set and makes slicing easier.
What’s the secret to perfect Cheesy Pepperoni Pizza Roll-Ups?
Using a thicker pizza sauce helps prevent sogginess and adds more flavor to each bite. You want that perfect balance of sauce to cheese without it turning into a gooey mess!
Can I make Cheesy Pepperoni Pizza Roll-Ups ahead of time?
Absolutely! You can prepare the roll-ups ahead and store them in the fridge. Just bake them right before serving for that fresh, hot texture that everyone loves.
How do I avoid common mistakes with Cheesy Pepperoni Pizza Roll-Ups?
Make sure not to overfill the tortillas to avoid spills while rolling. It’s best to be conservative with the amount of filling. Also, rolling too tightly can cause them to burst during baking, so keep it snug but not too tight!
Best Ways to Serve Cheesy Pepperoni Pizza Roll-Ups
When it comes to serving these delightful Cheesy Pepperoni Pizza Roll-Ups with Low-Carb Tortillas, presentation is key! Arrange the roll-ups on a vibrant platter and don’t forget to include a small bowl of extra pizza sauce for dipping—it’s a must! They make a fantastic snack all on their own, but for a complete meal, consider pairing them with a fresh side salad or crunchy veggie sticks for a nice contrast. If you’re hosting a gathering or a party, I love to set them out on a charcuterie board along with other fun finger foods and appetizers. It’s a surefire way to impress your guests and keep everyone coming back for more!
Nutrition Facts for Cheesy Pepperoni Pizza Roll-Ups
- Serving Size: 3-4 roll-ups
- Calories: 250
- Fat: 15g
- Saturated Fat: 7g
- Carbohydrates: 18g
- Fiber: 5g
- Protein: 15g
This nutritional information is an estimate and can vary based on ingredients used.

How to Store and Reheat Cheesy Pepperoni Pizza Roll-Ups
To keep your leftover Cheesy Pepperoni Pizza Roll-Ups with Low-Carb Tortillas fresh and tasty, store them in an airtight container in the fridge for up to 3 days. If you want to save them for later, freeze the roll-ups in a single layer on a baking sheet before transferring them to a freezer bag. This way, they won’t stick together, and you can easily grab a few at a time for up to 2 months. When it’s time to enjoy them again, simply bake the frozen roll-ups in the oven at 350°F for about 10 minutes until they’re heated through and crispy. If you’re in a hurry, you can use the microwave, but keep in mind that the texture might be a bit softer. Enjoy those cheesy bites!
Frequently Asked Questions About Cheesy Pepperoni Pizza Roll-Ups
- Can I use different tortillas for Cheesy Pepperoni Pizza Roll-Ups?
Yes, you can absolutely switch things up with whole wheat or gluten-free tortillas! Just keep in mind that this might alter the flavor and texture a bit, but it’s a great option if you have dietary preferences or restrictions. - What can I substitute for pepperoni?
If you’re looking for alternatives to classic pepperoni, you’re in luck! Turkey pepperoni is a lighter option, or you can opt for cooked sausage for a heartier flavor. You could even load them up with veggies like bell peppers or mushrooms for a delicious, healthier twist! - Are Cheesy Pepperoni Pizza Roll-Ups kid-friendly?
Oh, absolutely! Kids adore the cheesy goodness and the interactive fun of dipping them in pizza sauce. They’re perfect for lunchboxes or after-school snacks, making them a hit with little ones and adults alike! - Can I make them vegetarian?
Definitely! Just skip the pepperoni and load them up with your favorite veggies like spinach, zucchini, or even artichokes. You can still enjoy that cheesy, flavorful experience without the meat!
Variations of Cheesy Pepperoni Pizza Roll-Ups You Can Try
- Vegetarian Delight: Make them vegetarian by adding sliced bell peppers, mushrooms, and olives instead of pepperoni. It’s a colorful and tasty twist!
- Spicy Kick: For a spicy kick, add sliced jalapeños or use spicy pizza sauce to really amp up the flavor. Perfect for those who love a little heat!
- Cheese Blend: Experiment with different cheese blends, like sharp cheddar or zesty pepper jack, for varied flavors that will keep you coming back for more.
- Dessert Twist: Create a dessert version using low-carb tortillas filled with cream cheese and berries. It’s a sweet surprise that’s still low in carbs!
Check out more delicious recipes on our Pinterest!
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Cheesy Pepperoni Pizza Roll-Ups: 7 Reasons You’ll Love Them
- Prep Time: 10 minutes
- Cook Time: 12 minutes
- Total Time: 22 minutes
- Yield: 4 servings 1x
- Category: Snack
- Method: Baking
- Cuisine: American
- Diet: Low Calorie
Description
Cheesy Pepperoni Pizza Roll-Ups with Low-Carb Tortillas are a quick and easy snack or meal option. These roll-ups pack flavor and are perfect for those following a low-carb diet.
Ingredients
- 4 low-carb flour tortillas
- ½ cup pizza sauce, plus extra for dipping
- 1 cup shredded mozzarella cheese
- 16 slices pepperoni
- ½ teaspoon Italian seasoning
- Olive oil cooking spray (optional for crispiness)
Instructions
- Preheat your oven to 375°F and line a baking sheet with parchment paper to prevent sticking.
- Place all four tortillas flat on your work surface, making sure they’re at room temperature so they roll easily without cracking.
- Spread about 2 tablespoons of pizza sauce evenly on each tortilla, leaving a small border around the edges for rolling.
- Sprinkle ¼ cup of mozzarella cheese over the sauce on each tortilla, then arrange 4 pepperoni slices on top of the cheese.
- Sprinkle each tortilla with a pinch of Italian seasoning, then roll each one up tightly from one end to the other.
- Place the rolled tortillas seam-side down on your prepared baking sheet. Lightly spray the tops with olive oil if you want them extra crispy.
- Bake for 10-12 minutes until the cheese is melted and bubbly, and the tortillas are golden around the edges.
- Let the roll-ups cool for 2-3 minutes, then slice each one into 3-4 pieces using a sharp knife. Serve with extra pizza sauce for dipping.
Notes
- These roll-ups are great for meal prep.
- Feel free to add more toppings like vegetables or different cheeses.
- Store leftovers in an airtight container in the fridge.
Nutrition
- Serving Size: 3-4 roll-ups
- Calories: 250
- Sugar: 2g
- Sodium: 600mg
- Fat: 15g
- Saturated Fat: 7g
- Unsaturated Fat: 8g
- Trans Fat: 0g
- Carbohydrates: 18g
- Fiber: 5g
- Protein: 15g
- Cholesterol: 40mg
Keywords: Cheesy Pepperoni Pizza Roll-Ups, Low-carb tortillas, Pizza snacks